Tinkering under the Hood: Metabolic Optimisation of CAR-T Cell Therapy

Chimeric antigen receptor (CAR)-T cells are one of the most exciting areas of immunotherapy to date. Clinically available CAR-T cells are used to treat advanced haematological B-cell malignancies with complete remission achieved at around 30–40%. Unfortunately, CAR-T cell success rates are even less...

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Detalles Bibliográficos
Autores principales: Jenkins, Yasmin, Zabkiewicz, Joanna, Ottmann, Oliver, Jones, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167549/
https://www.ncbi.nlm.nih.gov/pubmed/33925949
http://dx.doi.org/10.3390/antib10020017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167549/
https://www.ncbi.nlm.nih.gov/pubmed/33925949
http://dx.doi.org/10.3390/antib10020017

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