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Tinkering under the Hood: Metabolic Optimisation of CAR-T Cell Therapy
Chimeric antigen receptor (CAR)-T cells are one of the most exciting areas of immunotherapy to date. Clinically available CAR-T cells are used to treat advanced haematological B-cell malignancies with complete remission achieved at around 30–40%. Unfortunately, CAR-T cell success rates are even less...
Autores principales: | Jenkins, Yasmin, Zabkiewicz, Joanna, Ottmann, Oliver, Jones, Nicholas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167549/ https://www.ncbi.nlm.nih.gov/pubmed/33925949 http://dx.doi.org/10.3390/antib10020017 |
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