Combining Mass Spectrometry-Based Phosphoproteomics with a Network-Based Approach to Reveal FLT3-Dependent Mechanisms of Chemoresistance

FLT3 mutations are the most frequently identified genetic alterations in acute myeloid leukemia (AML) and are associated with poor clinical outcome, relapse and chemotherapeutic resistance. Elucidating the molecular mechanisms underlying FLT3-dependent pathogenesis and drug resistance is a crucial g...

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Detalles Bibliográficos
Autores principales: Pugliese, Giusj Monia, Latini, Sara, Massacci, Giorgia, Perfetto, Livia, Sacco, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167576/
https://www.ncbi.nlm.nih.gov/pubmed/33925552
http://dx.doi.org/10.3390/proteomes9020019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167576/
https://www.ncbi.nlm.nih.gov/pubmed/33925552
http://dx.doi.org/10.3390/proteomes9020019

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