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Histone Sample Preparation for Bottom-Up Mass Spectrometry: A Roadmap to Informed Decisions

Histone-based chromatin organization enabled eukaryotic genome complexity. This epigenetic control mechanism allowed for the differentiation of stable gene-expression and thus the very existence of multicellular organisms. This existential role in biology makes histones one of the most complexly mod...

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Detalles Bibliográficos
Autores principales: Daled, Simon, Willems, Sander, Van Puyvelde, Bart, Corveleyn, Laura, Verhelst, Sigrid, De Clerck, Laura, Deforce, Dieter, Dhaenens, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167631/
https://www.ncbi.nlm.nih.gov/pubmed/33919160
http://dx.doi.org/10.3390/proteomes9020017