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Histone Sample Preparation for Bottom-Up Mass Spectrometry: A Roadmap to Informed Decisions
Histone-based chromatin organization enabled eukaryotic genome complexity. This epigenetic control mechanism allowed for the differentiation of stable gene-expression and thus the very existence of multicellular organisms. This existential role in biology makes histones one of the most complexly mod...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167631/ https://www.ncbi.nlm.nih.gov/pubmed/33919160 http://dx.doi.org/10.3390/proteomes9020017 |