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Small Mass but Strong Information: Diagnostic Ions Provide Crucial Clues to Correctly Identify Histone Lysine Modifications

(1) Background: The proteomic analysis of histones constitutes a delicate task due to the combination of two factors: slight variations in the amino acid sequences of variants and the multiplicity of post-translational modifications (PTMs), particularly those occurring on lysine residues. (2) Method...

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Detalles Bibliográficos
Autores principales: Hseiky, Alaa, Crespo, Marion, Kieffer-Jaquinod, Sylvie, Fenaille, François, Pflieger, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167651/
https://www.ncbi.nlm.nih.gov/pubmed/33922761
http://dx.doi.org/10.3390/proteomes9020018