Effect of Doxycycline Microencapsulation on Buccal Films: Stability, Mucoadhesion and In Vitro Drug Release

The aim of this work was to stabilize doxycycline in mucoadhesive buccal films at room temperature (25 °C). Since doxycycline is susceptible to degradation such as oxidation and epimerization, tablets are currently the only formulation that can keep the drug fully stable at room temperature, while l...

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Detalles Bibliográficos
Autores principales: Patlolla, Venu Gopal Reddy, Popovic, Nikolina, Peter Holbrook, William, Kristmundsdottir, Thordis, Gizurarson, Sveinbjörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167737/
https://www.ncbi.nlm.nih.gov/pubmed/33924744
http://dx.doi.org/10.3390/gels7020051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167737/
https://www.ncbi.nlm.nih.gov/pubmed/33924744
http://dx.doi.org/10.3390/gels7020051

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