Association Between Genetic Polymorphisms of Metabolic Enzymes and Azathioprine-Induced Myelosuppression in 1,419 Chinese Patients: A Retrospective Study

The aim of this study was to investigate the correlation between genetic polymorphisms of azathioprine-metabolizing enzymes and adverse reactions of myelosuppression. To this end, a retrospective analysis was performed on 1,419 Chinese patients involving 40 different diseases and 3 genes: ITPA (94C&...

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Detalles Bibliográficos
Autores principales: Chen, Zhao-Yang, Zhu, Yang-Hui, Zhou, Ling-Yan, Shi, Wei-Qiao, Qin, Zhou, Wu, Bin, Yan, Yu, Pei, Yu-Wen, Chao, Ning-Ning, Zhang, Rui, Wang, Mi-Ye, Su, Ze-Hao, Lu, Xiao-Jun, He, Zhi-Yao, Xu, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167793/
https://www.ncbi.nlm.nih.gov/pubmed/34084143
http://dx.doi.org/10.3389/fphar.2021.672769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167793/
https://www.ncbi.nlm.nih.gov/pubmed/34084143
http://dx.doi.org/10.3389/fphar.2021.672769

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