Discovery and Characterization of the Biflavones From Ginkgo biloba as Highly Specific and Potent Inhibitors Against Human Carboxylesterase 2

Human carboxylesterase 2 (CES2), one of the most abundant hydrolases distributed in the small intestine, has been validated as a key therapeutic target to ameliorate the intestinal toxicity caused by irinotecan. This study aims to discover efficacious CES2 inhibitors from natural products and to cha...

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Detalles Bibliográficos
Autores principales: Song, Yun-Qing, He, Rong-Jing, Pu, Dan, Guan, Xiao-Qing, Shi, Jin-Hui, Li, Yao-Guang, Hou, Jie, Jia, Shou-Ning, Qin, Wei-Wei, Fang, Sheng-Quan, Ge, Guang-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167799/
https://www.ncbi.nlm.nih.gov/pubmed/34084136
http://dx.doi.org/10.3389/fphar.2021.655659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167799/
https://www.ncbi.nlm.nih.gov/pubmed/34084136
http://dx.doi.org/10.3389/fphar.2021.655659

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