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Inhibition of MAGL activates the Keap1/Nrf2 pathway to attenuate glucocorticoid‐induced osteonecrosis of the femoral head

Glucocorticoids (GCs) are used in treating viral infections, acute spinal cord injury, autoimmune diseases, and shock. Several patients develop GC‐induced osteonecrosis of the femoral head (ONFH). However, the pathogenic mechanisms underlying GC‐induced ONFH remain poorly understood. GC‐directed bon...

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Detalles Bibliográficos
Autores principales: Yang, Ning, Sun, Houyi, Xue, Yi, Zhang, Weicheng, Wang, Hongzhi, Tao, Huaqiang, Liang, Xiaolong, Li, Meng, Xu, Yaozeng, Chen, Liang, Zhang, Liang, Huang, Lixin, Geng, Dechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167863/
https://www.ncbi.nlm.nih.gov/pubmed/34185425
http://dx.doi.org/10.1002/ctm2.447