Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb‐202 in gastric cancer

BACKGROUND: The main function of folate receptor α (FOLRα) has been considered to mediate intracellular folate uptake and induce tumor cell proliferation. Given the broad spectrum of expression among malignant tumors, including gastric cancer (GC) but not in normal tissue, FOLRα represents an attrac...

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Detalles Bibliográficos
Autores principales: Sakai, Hitomi, Kawakami, Hisato, Teramura, Takeshi, Onodera, Yuta, Somers, Elizabeth, Furuuchi, Keiji, Uenaka, Toshimitsu, Kato, Ryoji, Nakagawa, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167866/
https://www.ncbi.nlm.nih.gov/pubmed/34185411
http://dx.doi.org/10.1002/ctm2.454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167866/
https://www.ncbi.nlm.nih.gov/pubmed/34185411
http://dx.doi.org/10.1002/ctm2.454

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