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CRISPR‐based knock‐in mutagenesis of the pioneer transcription factor FOXA1: optimization of strategies for multi‐allelic proteins in cancer cells

Precise genome engineering of living cells has been revolutionized by the introduction of the highly specific and easily programmable properties of the clustered regularly interspaced short palindromic repeats (CRISPR) technology. This has greatly accelerated research into human health and has facil...

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Detalles Bibliográficos
Autores principales: Li, Shen, Garay, Joseph P., Tubbs, Colby A., Franco, Hector L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167868/
https://www.ncbi.nlm.nih.gov/pubmed/33666335
http://dx.doi.org/10.1002/2211-5463.13139