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Inflammatory activation of endothelial cells increases glycolysis and oxygen consumption despite inhibiting cell proliferation

Endothelial cell function and metabolism are closely linked to differential use of energy substrate sources and combustion. While endothelial cell migration is promoted by 2‐phosphofructokinase‐6/fructose‐2,6‐bisphosphatase (PFKFB3)‐driven glycolysis, proliferation also depends on fatty acid oxidati...

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Detalles Bibliográficos
Autores principales: Wik, Jonas Aakre, Phung, Danh, Kolan, Shrikant, Haraldsen, Guttorm, Skålhegg, Bjørn Steen, Hol Fosse, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167874/
https://www.ncbi.nlm.nih.gov/pubmed/33979025
http://dx.doi.org/10.1002/2211-5463.13174