Cargando…

Inflammatory activation of endothelial cells increases glycolysis and oxygen consumption despite inhibiting cell proliferation

Endothelial cell function and metabolism are closely linked to differential use of energy substrate sources and combustion. While endothelial cell migration is promoted by 2‐phosphofructokinase‐6/fructose‐2,6‐bisphosphatase (PFKFB3)‐driven glycolysis, proliferation also depends on fatty acid oxidati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wik, Jonas Aakre, Phung, Danh, Kolan, Shrikant, Haraldsen, Guttorm, Skålhegg, Bjørn Steen, Hol Fosse, Johanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167874/ https://www.ncbi.nlm.nih.gov/pubmed/33979025 http://dx.doi.org/10.1002/2211-5463.13174

Ejemplares similares

3PO inhibits inflammatory NFκB and stress-activated kinase signaling in primary human endothelial cells independently of its target PFKFB3
por: Wik, Jonas Aakre, et al.
Publicado: (2020)

Identification and characterization of a novel glutaminase inhibitor
por: Cederkvist, Henning, et al.
Publicado: (2021)

Activated, Pro-Inflammatory Th1, Th17, and Memory CD4+ T Cells and B Cells Are Involved in Delayed-Type Hypersensitivity Arthritis (DTHA) Inflammation and Paw Swelling in Mice
por: Li, Gaoyang, et al.
Publicado: (2021)

T Cell Metabolism in Infection
por: Wik, Jonas Aakre, et al.
Publicado: (2022)

Antibody blockade of Jagged1 attenuates choroidal neovascularization
por: Gjølberg, Torleif Tollefsrud, et al.
Publicado: (2023)

Endothelial Cells in Emerging Viral Infections
por: Fosse, Johanna Hol, et al.
Publicado: (2021)

Endogenous glutamine is rate-limiting for anti-CD3 and anti-CD28 induced CD4(+) T-cell proliferation and glycolytic activity under hypoxia and normoxia
por: Wik, Jonas A., et al.
Publicado: (2022)

Identification of SNPs associated with methotrexate treatment outcomes in patients with early rheumatoid arthritis
por: Kolan, Shrikant S., et al.
Publicado: (2022)

Regulation of glycolysis and oxygen consumption in lymph-node cells of normal and leukaemic mice.
por: Arany, I., et al.
Publicado: (1981)

Loss of interleukin 33 expression in colonic crypts - a potential marker for disease remission in ulcerative colitis
por: Gundersen, Mona Dixon, et al.
Publicado: (2016)

Normal Muscle Oxygen Consumption and Fatigability in Sickle Cell Patients Despite Reduced Microvascular Oxygenation and Hemorheological Abnormalities
por: Waltz, Xavier, et al.
Publicado: (2012)

ARGON, XENON, HYDROGEN, AND THE OXYGEN CONSUMPTION AND GLYCOLYSIS OF MOUSE TISSUE SLICES
por: South, Frank E., et al.
Publicado: (1954)

Nuclear IL-33 restrains the early conversion of fibroblasts to an extracellular matrix-secreting phenotype
por: Gatti, Francesca, et al.
Publicado: (2021)

The Molecular Basis for Specificity at the Level of the Protein Kinase a Catalytic Subunit
por: Søberg, Kristoffer, et al.
Publicado: (2018)

Statins Affect the Presentation of Endothelial Chemokines by Targeting to Multivesicular Bodies
por: Hol, Johanna, et al.
Publicado: (2012)

Rapid Secretion of Prestored Interleukin 8 from Weibel-Palade Bodies of Microvascular Endothelial Cells
por: Utgaard, Jon Olav, et al.
Publicado: (1998)

Oligomerized, filamentous surface presentation of RANTES/CCL5 on vascular endothelial cells
por: Øynebråten, Inger, et al.
Publicado: (2015)

Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa
por: Hereng, T.H., et al.
Publicado: (2011)

Th17 Polarization under Hypoxia Results in Increased IL-10 Production in a Pathogen-Independent Manner
por: Volchenkov, Roman, et al.
Publicado: (2017)

A novel somatic mutation in GNB2 provides new insights to the pathogenesis of Sturge–Weber syndrome
por: Fjær, Roar, et al.
Publicado: (2021)

Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer
por: Haabeth, Ole Audun Werner, et al.
Publicado: (2011)

Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms
por: Søberg, Kristoffer, et al.
Publicado: (2017)

High glycolysis in gliomas despite low hexokinase transcription and activity correlated to chromosome 10 loss.
por: Oudard, S., et al.
Publicado: (1996)

A role for CCR4 in development of mature circulating cutaneous T helper memory cell populations
por: Baekkevold, Espen S., et al.
Publicado: (2005)

Lack of interleukin-33 and its receptor does not prevent calcipotriol-induced atopic dermatitis-like inflammation in mice
por: Pietka, Wojciech, et al.
Publicado: (2020)

The Ccr7 Ligand ELC (Ccl19) Is Transcytosed in High Endothelial Venules and Mediates T Cell Recruitment
por: Baekkevold, Espen S., et al.
Publicado: (2001)

Fatty Acid Reference Intervals in Red Blood Cells among Pregnant Women in Norway–Cross Sectional Data from the ‘Little in Norway’ Cohort
por: Araujo, Pedro, et al.
Publicado: (2020)

South Asians Have Elevated Postexercise Blood Pressure and Myocardial Oxygen Consumption Compared to Europeans Despite Equivalent Resting Pressure
por: Chaturvedi, Nish, et al.
Publicado: (2012)

Contribution of proton leak to oxygen consumption in skeletal muscle during intense exercise is very low despite large contribution at rest
por: Korzeniewski, Bernard
Publicado: (2017)

Growth-inhibition of cell lines derived from B cell lymphomas through antagonism of serotonin receptor signaling
por: Kolan, Shrikant S., et al.
Publicado: (2019)

Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases
por: Christopoulos, Panagiotis F., et al.
Publicado: (2021)

Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen
por: Kolan, Shrikant Shantilal, et al.
Publicado: (2015)

Memory CD8(+) T cells upregulate glycolysis and effector functions under limiting oxygen conditions
por: Beumer‐Chuwonpad, Ammarina, et al.
Publicado: (2022)

Establishment and Characterization of a Novel Gill Cell Line, LG-1, from Atlantic Lumpfish (Cyclopterus lumpus L.)
por: Sindre, Hilde, et al.
Publicado: (2021)

Regulation of glycolysis in brown adipocytes by HIF-1α
por: Basse, Astrid L., et al.
Publicado: (2017)

Oxygen Consumption of the Aerobically-Perfused Cardioplegic Donor Heart at Different Temperatures
por: Qin, Guangqi, et al.
Publicado: (2018)

Sufficient iodine status among Norwegian toddlers 18 months of age – cross-sectional data from the Little in Norway study
por: Aakre, Inger, et al.
Publicado: (2018)

HMGB1 concentration measurements in trauma patients: assessment of pre-analytical conditions and sample material
por: Ottestad, William, et al.
Publicado: (2019)

Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis
por: Gundersen, Mona Dixon, et al.
Publicado: (2022)

The misery-is-not-miserly effect revisited: Replication despite opportunities for compensatory consumption
por: Garg, Nitika, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_h2ojk1m98n5qjahlc7bheb1jbv