Mutation of a conserved glutamine residue does not abolish desensitization of acid-sensing ion channel 1

Desensitization is a common feature of ligand-gated ion channels, although the molecular cause varies widely between channel types. Mutations that greatly reduce or nearly abolish desensitization have been described for many ligand-gated ion channels, including glutamate, GABA, glycine, and nicotini...

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Detalles Bibliográficos
Autores principales: Rook, Matthew L., Miaro, Megan, Couch, Tyler, Kneisley, Dana L., Musgaard, Maria, MacLean, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167889/
https://www.ncbi.nlm.nih.gov/pubmed/34061161
http://dx.doi.org/10.1085/jgp.202012855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167889/
https://www.ncbi.nlm.nih.gov/pubmed/34061161
http://dx.doi.org/10.1085/jgp.202012855

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