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Mutation of a conserved glutamine residue does not abolish desensitization of acid-sensing ion channel 1
Desensitization is a common feature of ligand-gated ion channels, although the molecular cause varies widely between channel types. Mutations that greatly reduce or nearly abolish desensitization have been described for many ligand-gated ion channels, including glutamate, GABA, glycine, and nicotini...
Autores principales: | Rook, Matthew L., Miaro, Megan, Couch, Tyler, Kneisley, Dana L., Musgaard, Maria, MacLean, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167889/ https://www.ncbi.nlm.nih.gov/pubmed/34061161 http://dx.doi.org/10.1085/jgp.202012855 |
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