Enhanced mPGES-1 Contributes to PD-Related Peritoneal Fibrosis via Activation of the NLRP3 Inflammasome

Background: Microsomal prostaglandin E synthase-1 (mPGES-1)-derived prostaglandin E(2) (PGE2) is a chief mediator of inflammation. However, the role and mechanism of mPGES-1 in peritoneal dialysis (PD)-associated peritoneal fibrosis have not been investigated. Material and Methods: In PD patients, m...

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Detalles Bibliográficos
Autores principales: Luo, Qimei, Hu, Qinghua, Zheng, Qingkun, Gong, Lewei, Su, Lijuan, Ren, Baojun, Ju, Yongle, Jia, Zhanjun, Dou, Xianrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167893/
https://www.ncbi.nlm.nih.gov/pubmed/34084773
http://dx.doi.org/10.3389/fmed.2021.675363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167893/
https://www.ncbi.nlm.nih.gov/pubmed/34084773
http://dx.doi.org/10.3389/fmed.2021.675363

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