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Enhanced mPGES-1 Contributes to PD-Related Peritoneal Fibrosis via Activation of the NLRP3 Inflammasome

Background: Microsomal prostaglandin E synthase-1 (mPGES-1)-derived prostaglandin E(2) (PGE2) is a chief mediator of inflammation. However, the role and mechanism of mPGES-1 in peritoneal dialysis (PD)-associated peritoneal fibrosis have not been investigated. Material and Methods: In PD patients, m...

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Detalles Bibliográficos
Autores principales:	Luo, Qimei, Hu, Qinghua, Zheng, Qingkun, Gong, Lewei, Su, Lijuan, Ren, Baojun, Ju, Yongle, Jia, Zhanjun, Dou, Xianrui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167893/ https://www.ncbi.nlm.nih.gov/pubmed/34084773 http://dx.doi.org/10.3389/fmed.2021.675363

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