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Hypoxic tumor-derived exosomal miR-31-5p promotes lung adenocarcinoma metastasis by negatively regulating SATB2-reversed EMT and activating MEK/ERK signaling

BACKGROUND: Exosomes have emerged as critical mediators of intercellular communication. Hypoxia is widely recognized as a key regulator of tumor aggressiveness, and significantly affects exosome release by tumor cells. However, the effects of exosomes derived from hypoxic lung adenocarcinoma (LUAD)...

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Detalles Bibliográficos
Autores principales:	Yu, Fengqiang, Liang, Mingqiang, Huang, Yu, Wu, Weidong, Zheng, Bin, Chen, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167983/ https://www.ncbi.nlm.nih.gov/pubmed/34074322 http://dx.doi.org/10.1186/s13046-021-01979-7

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