HGG-07. RADIATION INDUCED SENESCENCE IN DIFFUSE INTRINSIC PONTINE GLIOMA CELLS REVEALS SELECTIVE VULNERABILITY TO BCL-XL INHIBITION

Diffuse intrinsic pontine glioma remains a devastating condition with a dismal five year survival rate less than 5%. New approaches for treating this aggressive disease are critical to driving progress. Conventional radiotherapy remains the cornerstone of treatment, with no chemotherapeutic agent fo...

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Detalles Bibliográficos
Autores principales: Vardon, Ashley, Guiho, Romain, Carvalho, Diana, Jones, Chris, Hargrave, Darren, Martinez-Barbera, Juan-Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
High Grade Gliomas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168093/
http://dx.doi.org/10.1093/neuonc/noab090.073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168093/
http://dx.doi.org/10.1093/neuonc/noab090.073

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