IMMU-17. USE OF MRNA FOR SAFE AND EFFECTIVE GD2-DIRECTED CAR T CELLS TO TREAT DIFFUSE MIDLINE GLIOMAS

Chimeric antigen receptor (CAR) T cells targeting the disialoganglioside GD2 have garnered interest as an effective therapeutic for treating diffuse midline glioma (DMG). However, prior studies raised significant concerns of neurotoxicity and fatality when using virally transduced CAR T cells agains...

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Detalles Bibliográficos
Autores principales: Foster, Jessica, Griffin, Crystal, Stern, Allison, Brimley, Cameron, Storm, Phillip, Barrett, David, Resnick, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Immunology/Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168104/
http://dx.doi.org/10.1093/neuonc/noab090.124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168104/
http://dx.doi.org/10.1093/neuonc/noab090.124

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