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IMMU-13. CUSTOMIZABLE MULTI-LAMELLAR RNA-NANOPARTICLES FOR PEDIATRIC GLIOMA

BACKGROUND: Since the preponderance of pediatric gliomas are mutationally ‘bland,’ immune checkpoint inhibitors are unlikely to mediate therapeutic benefit. Alternately, immunologic response can be induced de novo against pediatric gliomas with mRNA cancer vaccines. Messenger RNA represents a paradi...

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Detalles Bibliográficos
Autores principales: Mendez-Gomez, Hector, McGuiness, James, grippin, Adam, Weidert, Frances, Carrera-Justiz, Sheila, Mitchell, Duane, Sayour, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168117/
http://dx.doi.org/10.1093/neuonc/noab090.120