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IMMU-13. CUSTOMIZABLE MULTI-LAMELLAR RNA-NANOPARTICLES FOR PEDIATRIC GLIOMA
BACKGROUND: Since the preponderance of pediatric gliomas are mutationally ‘bland,’ immune checkpoint inhibitors are unlikely to mediate therapeutic benefit. Alternately, immunologic response can be induced de novo against pediatric gliomas with mRNA cancer vaccines. Messenger RNA represents a paradi...
Autores principales: | Mendez-Gomez, Hector, McGuiness, James, grippin, Adam, Weidert, Frances, Carrera-Justiz, Sheila, Mitchell, Duane, Sayour, Elias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168117/ http://dx.doi.org/10.1093/neuonc/noab090.120 |
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