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OMIC-09. MAPPING THE HISTONE MUTATIONAL LANDSCAPE ACROSS ADULT AND PEDIATRIC CANCER GENOMES UNCOVERS NOVEL SOMATIC MUTATIONS IN PEDIATRIC HIGH-GRADE GLIOMAS

There is a growing role for mutations affecting histone linker and histone core-encoding genes across several adult and pediatric cancers. However, the extent to which somatic histone mutations may bridge across different cancers as common tumorigenic events – particularly in the context of pediatri...

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Detalles Bibliográficos
Autores principales: Bonner, Erin, Gaonkar, Krutika, Jain, Payal, Zhu, Yuankun, Laternser, Sandra, Eze, Augustine, Kambhampati, Madhuri, Yadavilli, Sridevi, Cain, Jason, Mueller, Sabine, Waszak, Sebastian, Nazarian, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168168/
http://dx.doi.org/10.1093/neuonc/noab090.156