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EPCT-07. ID1 IS A KEY TRANSCRIPTIONAL REGULATOR OF DIPG INVASION AND IS TARGETABLE WITH CANNABIDIOL

Diffuse intrinsic pontine gliomas (DIPGs) are lethal pediatric brain tumors with no effective therapies beyond radiation. The highly invasive nature of DIPG is key to its aggressive phenotype, but the factors and mechanisms contributing to this aggressive invasion are unknown. Inhibitor of DNA bindi...

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Detalles Bibliográficos
Autores principales: Nand Yadav, Viveka, Harris, Micah K, Thomas, Chase, Stallard, Stefanie, Woo, Rinette, Siddaway, Robert, Qin, Tingting, Cummings, Jessica R, Mullan, Brendan, Siada, Ruby, Ravindran, Ramya, Niculcea, Michael, Cao, Xuhong, Castro, Maria G, Lowenstein, Pedro R, Mody, Rajen, Chinnaiyan, Arul, Hawkins, Cynthia, Desprez, Pierre, McAllister, Sean, Venneti, Sriram, Koschmann, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168201/
http://dx.doi.org/10.1093/neuonc/noab090.193