SARS-CoV-2 Nsp14 activates NF-κB signaling and induces IL-8 upregulation

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to NF-κB activation and induction of pro-inflammatory cytokines, though the underlying mechanism for this activation is not fully understood. Our results reveal that the SARS-CoV-2 Nsp14 protein contributes to the viral act...

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Detalles Bibliográficos
Autores principales: Li, Taiwei, Kenney, Adam D., Liu, Helu, Fiches, Guillaume N., Zhou, Dawei, Biswas, Ayan, Que, Jianwen, Santoso, Netty, Yount, Jacob S., Zhu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168382/
https://www.ncbi.nlm.nih.gov/pubmed/34075374
http://dx.doi.org/10.1101/2021.05.26.445787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168382/
https://www.ncbi.nlm.nih.gov/pubmed/34075374
http://dx.doi.org/10.1101/2021.05.26.445787

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