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Combination of a Sindbis-SARS-CoV-2 spike vaccine and αOX40 antibody elicits protective immunity against SARS-CoV-2 induced disease and potentiates long-term SARS-CoV-2-specific humoral and T-cell immunity.

The COVID-19 pandemic caused by the coronavirus SARS-CoV-2 is a major global public threat. Currently, a worldwide effort has been mounted to generate billions of effective SARS-CoV-2 vaccine doses to immunize the world’s population at record speeds. However, there is still demand for alternative ef...

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Detalles Bibliográficos
Autores principales: Scaglione, Antonella, Opp, Silvana, Hurtado, Alicia, Lin, Ziyan, Pampeno, Christine, Noval, Maria G, Thannickal, Sara A., Stapleford, Kenneth A., Meruelo, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168399/
https://www.ncbi.nlm.nih.gov/pubmed/34075383
http://dx.doi.org/10.1101/2021.05.28.446009