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Retinoic acid induces NELFA‐mediated 2C‐like state of mouse embryonic stem cells associates with epigenetic modifications and metabolic processes in chemically defined media

OBJECTIVES: Mouse embryonic stem cells (ESCs) are derived from the inner cell mass of blastocyst‐stage embryos and cultured in different culture media with varied pluripotency. Sporadically, a small population of ESCs exhibit 2‐cell stage embryonic features in serum containing medium. However, wheth...

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Detalles Bibliográficos
Autores principales: Wang, Yanqiu, Na, Qin, Li, Xihe, Tee, Wee‐Wei, Wu, Baojiang, Bao, Siqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168409/
https://www.ncbi.nlm.nih.gov/pubmed/33960560
http://dx.doi.org/10.1111/cpr.13049