Maternal sevoflurane exposure induces temporary defects in interkinetic nuclear migration of radial glial progenitors in the fetal cerebral cortex through the Notch signalling pathway

OBJECTIVES: The effects of general anaesthetics on fetal brain development remain elusive. Radial glial progenitors (RGPs) generate the majority of neurons in developing brains. Here, we evaluated the acute alterations in RGPs after maternal sevoflurane exposure. METHODS: Pregnant mice were exposed...

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Detalles Bibliográficos
Autores principales: Jiang, Ming, Tang, Tianxiang, Liang, Xinyue, Li, Juchen, Qiu, Yue, Liu, Shiwen, Bian, Shan, Xie, Yunli, Fang, Fang, Cang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168415/
https://www.ncbi.nlm.nih.gov/pubmed/33955094
http://dx.doi.org/10.1111/cpr.13042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168415/
https://www.ncbi.nlm.nih.gov/pubmed/33955094
http://dx.doi.org/10.1111/cpr.13042

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