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Maternal sevoflurane exposure induces temporary defects in interkinetic nuclear migration of radial glial progenitors in the fetal cerebral cortex through the Notch signalling pathway
OBJECTIVES: The effects of general anaesthetics on fetal brain development remain elusive. Radial glial progenitors (RGPs) generate the majority of neurons in developing brains. Here, we evaluated the acute alterations in RGPs after maternal sevoflurane exposure. METHODS: Pregnant mice were exposed...
Autores principales: | Jiang, Ming, Tang, Tianxiang, Liang, Xinyue, Li, Juchen, Qiu, Yue, Liu, Shiwen, Bian, Shan, Xie, Yunli, Fang, Fang, Cang, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168415/ https://www.ncbi.nlm.nih.gov/pubmed/33955094 http://dx.doi.org/10.1111/cpr.13042 |
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