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PTH‐induced EndMT via miR‐29a‐5p/GSAP/Notch1 pathway contributed to valvular calcification in rats with CKD

BACKGROUND: Endothelial‐to‐mesenchymal transition (EndMT) is a common pathophysiology in valvular calcification (VC) among non‐chronic kidney disease (CKD) patients. However, few studies were investigated in CKD‐induced VC. Parathyroid hormone (PTH) was considered to be an important component of End...

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Detalles Bibliográficos
Autores principales: Wang, Liting, Tang, Rining, Zhang, Yuxia, Chen, Sijie, Guo, Yu, Wang, Xiaochen, Liu, Zixiao, Liu, Hong, Zhang, Xiaoliang, Liu, Bi‐Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168417/
https://www.ncbi.nlm.nih.gov/pubmed/33945189
http://dx.doi.org/10.1111/cpr.13018