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PTH‐induced EndMT via miR‐29a‐5p/GSAP/Notch1 pathway contributed to valvular calcification in rats with CKD
BACKGROUND: Endothelial‐to‐mesenchymal transition (EndMT) is a common pathophysiology in valvular calcification (VC) among non‐chronic kidney disease (CKD) patients. However, few studies were investigated in CKD‐induced VC. Parathyroid hormone (PTH) was considered to be an important component of End...
Autores principales: | Wang, Liting, Tang, Rining, Zhang, Yuxia, Chen, Sijie, Guo, Yu, Wang, Xiaochen, Liu, Zixiao, Liu, Hong, Zhang, Xiaoliang, Liu, Bi‐Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168417/ https://www.ncbi.nlm.nih.gov/pubmed/33945189 http://dx.doi.org/10.1111/cpr.13018 |
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