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Substrate Stiffness Regulates Cholesterol Efflux in Smooth Muscle Cells

The infiltration and deposition of cholesterol in the arterial wall play an important role in the initiation and development of atherosclerosis. Smooth muscle cells (SMCs) are the major cell type in the intima. Upon exposure to cholesterol, SMCs may undergo a phenotype switching into foam cells. Mea...

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Detalles Bibliográficos
Autores principales: Mao, Xiuli, Tan, Yiling, Wang, Huali, Li, Song, Zhou, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168435/
https://www.ncbi.nlm.nih.gov/pubmed/34084769
http://dx.doi.org/10.3389/fcell.2021.648715