SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative pathogen of current COVID-19 pandemic, and insufficient production of type I interferon (IFN-I) is associated with the severe forms of the disease. Membrane (M) protein of SARS-CoV-2 has been reported to suppress host...

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Detalles Bibliográficos
Autores principales: Sui, Liyan, Zhao, Yinghua, Wang, Wenfang, Wu, Ping, Wang, Zedong, Yu, Yang, Hou, Zhijun, Tan, Guangyun, Liu, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168463/
https://www.ncbi.nlm.nih.gov/pubmed/34084167
http://dx.doi.org/10.3389/fimmu.2021.662989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168463/
https://www.ncbi.nlm.nih.gov/pubmed/34084167
http://dx.doi.org/10.3389/fimmu.2021.662989

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