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SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative pathogen of current COVID-19 pandemic, and insufficient production of type I interferon (IFN-I) is associated with the severe forms of the disease. Membrane (M) protein of SARS-CoV-2 has been reported to suppress host...
Autores principales: | Sui, Liyan, Zhao, Yinghua, Wang, Wenfang, Wu, Ping, Wang, Zedong, Yu, Yang, Hou, Zhijun, Tan, Guangyun, Liu, Quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168463/ https://www.ncbi.nlm.nih.gov/pubmed/34084167 http://dx.doi.org/10.3389/fimmu.2021.662989 |
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