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Granulocyte colony-stimulating factor directly acts on mouse lymphoid-biased but not myeloid-biased hematopoietic stem cells

Granulocyte colony-stimulating factor (G-CSF) is widely used in clinical settings to mobilize hematopoietic stem cells (HSC) into the circulation for HSC harvesting and transplantation. However, whether G-CSF directly stimulates HSC to change their cell cycle state and fate is controversial. HSC are...

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Detalles Bibliográficos
Autores principales: Xie, Miner, Zhang, Shanshan, Dong, Fang, Zhang, Qingyun, Wang, Jinhong, Wang, Chenchen, Zhu, Caiying, Zhang, Sen, Luo, Bingqing, Wu, Peng, Ema, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168498/
https://www.ncbi.nlm.nih.gov/pubmed/32079694
http://dx.doi.org/10.3324/haematol.2019.239251