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Whole-slide image analysis of the tumor microenvironment identifies low B-cell content as a predictor of adverse outcome in patients with advanced-stage classical Hodgkin lymphoma treated with BEACOPP

Asubset of patients with advanced-stage classical Hodgkin lymphoma (cHL) relapse or progress following standard treatment. Given their dismal prognosis, identifying this group of patients upfront represents an important medical need. While prior research has identified characteristics of the tumor m...

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Detalles Bibliográficos
Autores principales: Jachimowicz, Ron Daniel, Pieper, Luise, Reinke, Sarah, Gontarewicz, Artur, Plütschow, Annette, Haverkamp, Heinz, Frauenfeld, Leonie, Fend, Falko, Overkamp, Mathis, Jochims, Franziska, Thorns, Christoph, Leo Hansmann, Martin, Möller, Peter, Rosenwald, Andreas, Stein, Harald, Reinhardt, Hans Christian, Borchmann, Peter, von Tresckow, Bastian, Engert, Andreas, Klapper, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168506/
https://www.ncbi.nlm.nih.gov/pubmed/32381573
http://dx.doi.org/10.3324/haematol.2019.243287