Protein neddylation as a therapeutic target in pulmonary and extrapulmonary small cell carcinomas

Small cell lung carcinoma (SCLC) is among the most lethal of all solid tumor malignancies. In an effort to identify novel therapeutic approaches for this recalcitrant cancer type, we applied genome-scale CRISPR/Cas9 inactivation screens to cell lines that we derived from a murine model of SCLC. SCLC...

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Detalles Bibliográficos
Autores principales: Norton, Justin P., Augert, Arnaud, Eastwood, Emily, Basom, Ryan, Rudin, Charles M., MacPherson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168556/
https://www.ncbi.nlm.nih.gov/pubmed/34016692
http://dx.doi.org/10.1101/gad.348316.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168556/
https://www.ncbi.nlm.nih.gov/pubmed/34016692
http://dx.doi.org/10.1101/gad.348316.121

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