Interpretation of allele-specific chromatin accessibility using cell state–aware deep learning

Genomic sequence variation within enhancers and promoters can have a significant impact on the cellular state and phenotype. However, sifting through the millions of candidate variants in a personal genome or a cancer genome, to identify those that impact cis-regulatory function, remains a major cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Atak, Zeynep Kalender, Taskiran, Ibrahim Ihsan, Demeulemeester, Jonas, Flerin, Christopher, Mauduit, David, Minnoye, Liesbeth, Hulselmans, Gert, Christiaens, Valerie, Ghanem, Ghanem-Elias, Wouters, Jasper, Aerts, Stein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168584/
https://www.ncbi.nlm.nih.gov/pubmed/33832990
http://dx.doi.org/10.1101/gr.260851.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168584/
https://www.ncbi.nlm.nih.gov/pubmed/33832990
http://dx.doi.org/10.1101/gr.260851.120

Ejemplares similares