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Interpretation of allele-specific chromatin accessibility using cell state–aware deep learning

Genomic sequence variation within enhancers and promoters can have a significant impact on the cellular state and phenotype. However, sifting through the millions of candidate variants in a personal genome or a cancer genome, to identify those that impact cis-regulatory function, remains a major cha...

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Detalles Bibliográficos
Autores principales:	Atak, Zeynep Kalender, Taskiran, Ibrahim Ihsan, Demeulemeester, Jonas, Flerin, Christopher, Mauduit, David, Minnoye, Liesbeth, Hulselmans, Gert, Christiaens, Valerie, Ghanem, Ghanem-Elias, Wouters, Jasper, Aerts, Stein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2021
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168584/ https://www.ncbi.nlm.nih.gov/pubmed/33832990 http://dx.doi.org/10.1101/gr.260851.120

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