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Targeted single-cell RNA sequencing of transcription factors enhances the identification of cell types and trajectories

Single-cell RNA sequencing (scRNA-seq) is a widely used method for identifying cell types and trajectories in biologically heterogeneous samples, but it is limited in its detection and quantification of lowly expressed genes. This results in missing important biological signals, such as the expressi...

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Detalles Bibliográficos
Autores principales: Pokhilko, Alexandra, Handel, Adam E., Curion, Fabiola, Volpato, Viola, Whiteley, Emma S., Bøstrand, Sunniva, Newey, Sarah E., Akerman, Colin J., Webber, Caleb, Clark, Michael B., Bowden, Rory, Cader, M. Zameel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168586/
https://www.ncbi.nlm.nih.gov/pubmed/34011578
http://dx.doi.org/10.1101/gr.273961.120