Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2

The identification of CD4(+) T cell epitopes is instrumental for the design of subunit vaccines for broad protection against coronaviruses. Here we demonstrate in COVID-19-recovered individuals a robust CD4(+) T cell response to naturally processed SARS-CoV-2 spike (S) and nucleoprotein (N), includi...

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Detalles Bibliográficos
Autores principales: Low, Jun Siong, Vaqueirinho, Daniela, Mele, Federico, Foglierini, Mathilde, Jerak, Josipa, Perotti, Michela, Jarrossay, David, Jovic, Sandra, Perez, Laurent, Cacciatore, Rosalia, Terrot, Tatiana, Pellanda, Alessandra Franzetti, Biggiogero, Maira, Garzoni, Christian, Ferrari, Paolo, Ceschi, Alessandro, Lanzavecchia, Antonio, Sallusto, Federica, Cassotta, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168615/
https://www.ncbi.nlm.nih.gov/pubmed/34006597
http://dx.doi.org/10.1126/science.abg8985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168615/
https://www.ncbi.nlm.nih.gov/pubmed/34006597
http://dx.doi.org/10.1126/science.abg8985

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