Cargando…

Lipid signalling enforces T(reg) cell functional specialization in tumours

Regulatory T (T(reg)) cells are essential for immune tolerance1 but also drive immunosuppression in the tumour microenvironment (TME)2. Therapeutic targeting of T(reg) cells in cancer requires the identification of context-specific mechanisms for T(reg) cell function. Here we demonstrate that inhibi...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Seon Ah, Wei, Jun, Nguyen, Thanh-Long M., Shi, Hao, Su, Wei, Palacios, Gustavo, Dhungana, Yogesh, Chapman, Nicole M., Long, Lingyun, Saravia, Jordy, Vogel, Peter, Chi, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168716/
https://www.ncbi.nlm.nih.gov/pubmed/33627871
http://dx.doi.org/10.1038/s41586-021-03235-6