Protective effects of carbonic anhydrase inhibition in brain ischaemia in vitro and in vivo models

Ischaemic stroke is a leading cause of death and disability. One of the major pathogenic mechanisms after ischaemia includes the switch to the glycolytic pathway, leading to tissue acidification. Carbonic anhydrase (CA) contributes to pH regulation. A new generation of CA inhibitors, AN11-740 and AN...

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Detalles Bibliográficos
Autores principales: Dettori, Ilaria, Fusco, Irene, Bulli, Irene, Gaviano, Lisa, Coppi, Elisabetta, Cherchi, Federica, Venturini, Martina, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Nocentini, Alessio, Supuran, Claudiu T., Pugliese, Anna Maria, Pedata, Felicita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168743/
https://www.ncbi.nlm.nih.gov/pubmed/34056989
http://dx.doi.org/10.1080/14756366.2021.1907575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168743/
https://www.ncbi.nlm.nih.gov/pubmed/34056989
http://dx.doi.org/10.1080/14756366.2021.1907575

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