Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers

Herein, a new wave of bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives have been successfully designed and synthesised. The synthesised derivatives were biologically investigated for their cytotoxic activities against HepG2 and MCF-7. Also, the tested compounds were further exa...

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Detalles Bibliográficos
Autores principales: Alsaif, Nawaf A., Taghour, Mohammed S., Alanazi, Mohammed M., Obaidullah, Ahmad J., Al-Mehizia, Abdulrahman A., Alanazi, Manal M., Aldawas, Saleh, Elwan, Alaa, Elkady, Hazem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168755/
https://www.ncbi.nlm.nih.gov/pubmed/34056992
http://dx.doi.org/10.1080/14756366.2021.1915303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168755/
https://www.ncbi.nlm.nih.gov/pubmed/34056992
http://dx.doi.org/10.1080/14756366.2021.1915303

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