Mycobacterium tuberculosis sterilizing activity of faropenem, pyrazinamide and linezolid combination and failure to shorten the therapy duration

BACKGROUND: Faropenem (F), an orally bioavailable β-lactam, kills Mycobacterium tuberculosis (Mtb) without the help of a β-lactamase inhibitor. This study explored the sterilizing effect of adding F once or twice daily to a linezolid (L) plus pyrazinamide (Z) backbone regimen. METHODS: In vitro stud...

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Detalles Bibliográficos
Autores principales: Gumbo, Tawanda, Sherman, Carleton M., Deshpande, Devyani, Alffenaar, Jan-Willem, Srivastava, Shashikant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168785/
https://www.ncbi.nlm.nih.gov/pubmed/33556616
http://dx.doi.org/10.1016/j.ijid.2021.01.062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168785/
https://www.ncbi.nlm.nih.gov/pubmed/33556616
http://dx.doi.org/10.1016/j.ijid.2021.01.062

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