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Identification and functional analysis of a galactosyltransferase capable of cholesterol glycolipid formation in the Lyme disease spirochete Borrelia burgdorferi

Borrelia burgdorferi (Bb), the etiological agent of Lyme disease, produces a series of simple glycolipids where diacylglycerol and cholesterol serve as the precursor. The cholesterol-based glycolipids, cholesteryl 6-O-acyl-β-D-galactopyranoside (ACGal) and cholesteryl-β-D-galactopyranoside (CGal) ar...

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Detalles Bibliográficos
Autores principales: Hove, Petronella R., Magunda, Forgivemore, de Mello Marques, Maria Angela, Islam, M. Nurul, Harton, Marisa R., Jackson, Mary, Belisle, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168883/
https://www.ncbi.nlm.nih.gov/pubmed/34061884
http://dx.doi.org/10.1371/journal.pone.0252214