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TGF-β inhibition can overcome cancer primary resistance to PD-1 blockade: A mathematical model
Immune checkpoint inhibitors have demonstrated, over the recent years, impressive clinical response in cancer patients, but some patients do not respond at all to checkpoint blockade, exhibiting primary resistance. Primary resistance to PD-1 blockade is reported to occur under conditions of immunosu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168900/ https://www.ncbi.nlm.nih.gov/pubmed/34061898 http://dx.doi.org/10.1371/journal.pone.0252620 |