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Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer’s disease

Beta-amyloid (Aβ) and tau proteins, the pathological hallmarks of Alzheimer’s disease (AD), are believed to spread through connected regions of the brain. Combining diffusion imaging and positron emission tomography, we investigated associations between white matter microstructure specifically in bu...

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Detalles Bibliográficos
Autores principales: Pichet Binette, Alexa, Theaud, Guillaume, Rheault, François, Roy, Maggie, Collins, D Louis, Levin, Johannes, Mori, Hiroshi, Lee, Jae Hong, Farlow, Martin Rhys, Schofield, Peter, Chhatwal, Jasmeer P, Masters, Colin L, Benzinger, Tammie, Morris, John, Bateman, Randall, Breitner, John CS, Poirier, Judes, Gonneaud, Julie, Descoteaux, Maxime, Villeneuve, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169107/
https://www.ncbi.nlm.nih.gov/pubmed/33983116
http://dx.doi.org/10.7554/eLife.62929