Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology

Traumatic brain injury (TBI) is a predisposing factor for many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD), Parkinson’s disease (PD), and chronic traumatic encephalopathy (CTE). Although defects in nucleocytoplasmic transport (NCT) is reported...

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Detalles Bibliográficos
Autores principales: Anderson, Eric N, Morera, Andrés A, Kour, Sukhleen, Cherry, Jonathan D, Ramesh, Nandini, Gleixner, Amanda, Schwartz, Jacob C, Ebmeier, Christopher, Old, William, Donnelly, Christopher J, Cheng, Jeffrey P, Kline, Anthony E, Kofler, Julia, Stein, Thor D, Pandey, Udai Bhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169113/
https://www.ncbi.nlm.nih.gov/pubmed/34060470
http://dx.doi.org/10.7554/eLife.67587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169113/
https://www.ncbi.nlm.nih.gov/pubmed/34060470
http://dx.doi.org/10.7554/eLife.67587

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