A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma

We previously used a pulse-based in vitro assay to unveil targetable signalling pathways associated with innate cisplatin resistance in lung adenocarcinoma (Hastings et al., 2020). Here, we advanced this model system and identified a non-genetic mechanism of resistance that drives recovery and regro...

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Detalles Bibliográficos
Autores principales: Gonzalez Rajal, Alvaro, Marzec, Kamila A, McCloy, Rachael A, Nobis, Max, Chin, Venessa, Hastings, Jordan F, Lai, Kaitao, Kennerson, Marina, Hughes, William E, Vaghjiani, Vijesh, Timpson, Paul, Cain, Jason E, Watkins, D Neil, Croucher, David R, Burgess, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169122/
https://www.ncbi.nlm.nih.gov/pubmed/33983115
http://dx.doi.org/10.7554/eLife.65234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169122/
https://www.ncbi.nlm.nih.gov/pubmed/33983115
http://dx.doi.org/10.7554/eLife.65234

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